.Yes, I was using a few mods. I was able to narrow it down to "Crushing Industry - All Recipes and Crushers " with the setting "Restore Vanilla Recipes as Default" enabled. It looks like all 3 mods want to overwrite the vanilla recipe, causing the issue. Disabling the setting (which is default) fixes the issue, but I really liked the mod for allowing both vanilla and the modded application.
I found it very amusing we both came to the same conclusion for the balance.
As an aside, it is sad the Biochamber doesn't get to help out in this crafting chain. The poor thing gets left out of almost all the fun mods. The Cryogenic plant is way better with modules however....